BUTISOL SODIUM® (butabarbital sodium tablets, USP and butabarbital sodium oral Alternative, USP) is the sodium salt of a weak acid. Barbiturates are weak acids which can be absorbed and fast dispersed to all tissues and fluids with superior concentrations while in the brain, liver, and kidneys.
butabarbital will lower the level or influence of diltiazem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
butabarbital will reduce the level or result of diclofenac by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Significance Unknown.
butabarbital will lower the level or influence of estradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
butabarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral method of both brokers. Slight/Significance Mysterious.
butabarbital will lower the level or outcome of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Anticoagulant dose decreases may be required next barbiturate discontinuation or dose reduction. Take into account therapy modification
Barbiturates might cause fetal hurt when administered to your pregnant lady. Retrospective, case-controlled studies have suggested a connection involving the maternal use of barbiturates and a higher than expected incidence of fetal abnormalities.
butabarbital will decrease the extent or influence of buprenorphine, long-performing injection by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Sufferers who transfer to buprenorphine lengthy-performing injection from transmucosal buprenorphine coadministered with CYP3A4 inducers really should be monitored to be certain buprenorphine plasma stages are enough.
butabarbital will minimize the extent or effect of disopyramide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Mysterious.
This medication may possibly lead to accidental overdose and death if taken by other adults, children, or Animals. Mix any unused drugs with a substance like click here cat litter or coffee grounds.
butabarbital will minimize the extent or outcome of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.
butabarbital will reduce the level or outcome of felodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
MAOI prolong the consequences of barbiturates most likely because metabolism in the barbiturate is inhibited.